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  • Headache Disorders

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    An Introduction to Headache Disorders

    Headache disorders are among the most prevalent and incapacitating conditions worldwide, accounting for nearly three-quarters of all neurological-related disabilities. Primary headache disorders encompass migraine, tension headache, and cluster headache, while medication-overuse headache stands as the prevailing form of secondary headache. Over the past decade, significant advancements in headache management have emerged, revolutionizing the treatment landscape. Notably, novel therapeutic approaches have honed in on targeting the CGRP (calcitonin gene-related peptide) ligand or receptor, thereby reshaping the treatment paradigm for migraines and exhibiting efficacy in combatting cluster headache. Additionally, a fresh avenue of intervention comes in the form of ditans, gepants and monoclonal antibodies, with many forms of medications being delivered by different approaches such as skin patches and nasal sprays, thereby reducing patient burden. These breakthroughs hold great promise in alleviating the burden of headache disorders, fostering improved quality of life for affected individuals.

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