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Faculty & Disclosures
Dr Sam Amin

University Hospitals Bristol NHS Foundation Trust, Bristol, UK

Dr Sam Amin is a consultant paediatric neurologist and head of department at University Hospitals Bristol and Weston NHS Foundation Trust. He is chair of the South and Wales TSC network and has led several national and international working groups for guidelines in TSC. He runs an active research group in paediatric neurology and is chief investigator on nine current studies.

Dr Amin has received funding from GW Pharmaceuticals/Jazz Pharmaceuticals, Norvartis, PTC Therapeutics, Boston Scientific, Nutricia, UCB, BioMarin, LivaNova, Medtronic, Desitin, Ipsen, Orion, CDKL5 UK, TSA and the National Institute for Health Research.
Dr Milka Pringsheim

Epilepsy Center for Children and Adolescents, Schön Clinic Vogtareuth, Voiturette, Germany

Dr Milka Pringsheim has specialised in paediatric cardiology and neuropaediatrics. She has worked in the German Heart Centre Munich (Germany), as a paediatric cardiologist for 15 years, seeing outpatients with congenital heart disease and neurologic complications. She has also worked in the Schön Klinik Vogtareuth as a neuropaediatrician for 10 years, leading the ward for ICU there (intermediate care) and taking care of neuropaediatric patients with severe encephalopathy, who sometimes are also dependent on ventilation. In the neuropaediatric epilepsy centre, she is responsible for the cardiac investigations of the TSC patients. Her research focuses on genetic epilepsy syndromes.

Dr Pringsheim has previously received honoraria for speaking from Zogenix. She is part of the advisory board for Jazz Pharmaceuticals, Takeda and Zogenix.
Dr Nicholas Annear

St George's University Hospitals NHS Foundation Trust, London, UK

Dr Nicholas Annear is a Consultant in Acute Medicine and Nephrology St George’s University Hospitals. He undertakes specialist clinics in Acute Kidney Injury and Renal Transplantation, and established a new clinic for patients with TSC. He is also an Honorary Senior Lecturer in the Institute for Medical and Biomedical Teaching at St George’s University of London.

Dr Annear has been awarded research grants with the National Institute for Health Research (NIHR), the Wellcome Trust, the Imperial College Biomedical Research Centre, King’s College London Biomedical Research Centre and the Kathleen Valley Charitable Trust (KVCT). He is a co-signatory to a joint working project with Novartis to develop the TSC service at St George’s University Hospitals NHS Foundation Trust. He has previously received honoraria and educational grants for speaking, attending conferences and participating in research from Novartis and Vifor Pharma. He currently holds consulting agreements with Aeovian Pharmaceuticals and GW Pharmaceuticals/Jazz Pharmaceuticals.
Dr Aglaia Vignoli

University of Milan, Milan, Italy

Dr Aglaia Vignoli is Director of the Child Neurology and Psychiatry in Milan and assistant professor at the University of Milan. She has expertise in rare disorders and epilepsy and has led several research projects on rare disorders with neurologic impairment.

Dr Vignoli has received fees from Jazz Pharmaceuticals.
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    EUROPEAN PARTNER

    An Introduction to Epilepsy

    Epilepsy is one of the most common neurological disorders, affecting around 50 million people worldwide. Advances in epilepsy imaging and treatment (e.g. ablative and neurostimulation procedures, and new antiepileptic drugs) have decreased seizure frequency and severity. Yet unmet needs remain with approximately 30% of people with epilepsy refractory to pharmacotherapies. Novel therapeutic targets include AMPA receptors, potassium channels and synaptic vesicle protein 2A. Ongoing developments and improved understanding of the genetics of epilepsy subtypes may provide patient-specific solutions.

    Browse video highlights and short articles from the conference hub, providing insights into the latest updates from major conferences and peer-reviewed articles from our journal touchREVIEWS in Neurology. This is complimented by a range of educational activities developed in collaboration with our leading expert faculty.

    Our supporting partners do not constitute an endorsement of the content on this page.

    Epilepsy Content

    touchTEAMS
    The typical patient journey in tuberous sclerosis complex and unmet needs
    For HCPs in: Europe
    View Time: 52 mins Sponsored content

    Sponsored content by Jazz Pharmaceuticals. Watch leading tuberous sclerosis complex (TSC) experts discuss the heterogenous presentation of the disease, typical referral and management pathways and unmet needs.

     

    INT-NEU-2300042
    Date of Preparation: November 2023
    Epilepsy, Headache Disorders, Multiple Sclerosis, Neuroimmunology, Neuromuscular Diseases, Parkinson's Disease
    Developed by Touch
    Highlights from EAN 2023!
    Watch Time: 2 mins

    Epilepsy
    Developed by Touch
    Jacqueline French, AAN 2023: XEN1101, a novel potassium channel modulator for the treatment of focal epilepsy
    Watch Time: 03:52

    In this interview with touchNEUROLOGY, Prof. Jacqueline French (Comprehensive Epilepsy Center, New York University, New York, NY, US) discusses the needs of adults with focal epilepsy and the mechanisms of action of XEN1101, a novel, potent, selective Kv7.2/7.3 potassium channel. The abstract entitled “XEN1101, a Novel Potassium Channel Modulator: Interim Data From an Ongoing, Long-Term, […]

    Epilepsy
    Developed by Touch
    Jacqueline French, AAN 2023: X-TOLE phase 2b open-label extension trial of XEN1101 in focal epilepsy – interim data
    Watch Time: 07:57

    The randomized, double-blind, placebo-controlled phase IIb study X-TOLE (NCT03796962) is investigating the efficacy of XEN1101, a novel potassium channel modulator, in adults with focal epilepsy.   In this interview with touchNEUROLOGY, Prof. Jacqueline French (Comprehensive Epilepsy Center, New York University, New York, NY, US) discusses this clinical trial and the outcomes of its open-label extension.  The […]

    Epilepsy, Paediatric Neurology, Rare Diseases
    Watch Time: 34 mins
    touchMDT
    Improving outcomes for patients with tuberous sclerosis complex-associated seizures: Integrating new treatment options into existing care pathways
    CE/CME ACCREDITED Prof. James Wheless, Prof. Katarzyna Kotulska, Ms Lisa Moss Translations available:

    MDT specialists and a caregiver of a patient with tuberous sclerosis complex (TSC) discuss current and emerging management strategies for TSC-associated seizures.

    Learning objectives
    Learning Objectives
    • Discuss the burden of TSC for patients and caregivers, and explore how TSC-associated seizures are currently managed
    • Assess existing and emerging treatment options for TSC-associated seizures including their impact on seizure prevention and delay in onset
    • Evaluate to what extent current treatment challenges and knowledge gaps in TSC-associated seizures impact clinical practice
    Epilepsy, Headache Disorders, Movement Disorders, Paediatric Neurology
    A Bird in the Hand: A Neurologist’s Guide to Efficient Tweeting in the Age of Social Media
    Divyani Garg, Ayush Agarwal, Venugopalan Y Vishnu

    touchREVIEWS in Neurology 2022;18(2):76–80 DOI: https://doi.org/10.17925/USN.2022.18.2.76

    The surge in social media use seems to have become a sign of our times. Social media has ramified into not only our personal lives but, importantly, also our professional lives and will continue to do so in the future.1–4 At the same time, more neurologists resorted to online learning modalities, including podcasts and social media […]

    Epilepsy, Paediatric Neurology, Rare Diseases
    Developed by Touch
    Galia Wilson, Dravet Syndrome UK: DSUK Objectives, directions and support for families and people living with Dravet syndrome
    Watch Time: 19 mins

    Dravet Syndrome (DS) is a rare neurological condition, beginning in infancy and lasting a lifetime. touchNEUROLOGY were joined by Galia Wilson, Chair and Trustee of Dravet Syndrome UK (DSUK), a charity created in 2008 by a group of parents who came together looking for support, resources and information relating to the neurological condition. In this interview, […]

    Epilepsy, Paediatric Neurology, Rare Diseases
    Galia Wilson, Dravet Syndrome UK: Dravet syndrome, and the impact on daily life for patients, families and caregivers
    Watch Time: 11 mins

    Dravet Syndrome (DS) is a rare neurological condition, beginning in infancy and lasting a lifetime. The impact and the constant care required for someone living with DS has on the patient and their family’s quality of life can be huge. touchNEUROLOGY are joined by Galia Wilson, Chair and Trustee of Dravet Syndrome UK (DSUK), a […]

    Epilepsy, Paediatric Neurology, Rare Diseases
    Developed by Touch
    Galia Wilson, Dravet Syndrome UK: Unmet needs in the diagnosis and treatment of Dravet syndrome

    Dravet Syndrome (DS) is a rare neurological condition, beginning in infancy and lasting a lifetime. touchNEUROLOGY were joined by Galia Wilson, Chair and Trustee of Dravet Syndrome UK (DSUK), a charity created in 2008 by a group of parents who came together looking for support, resources and information relating to the neurological condition. Galia discusses unmet […]

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