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    • Stroke

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    An Introduction to Stroke

    Most strokes (85%) are caused by acute ischaemia due to blockage of a cerebral artery, leading to loss of oxygenation in downstream brain tissue, and ultimately causing neuronal cell death and irreversible neurological damage. The remainder are haemorrhagic strokes, caused by intracerebral or subarachnoid haemorrhage. Treatment of ischaemic stroke has been transformed by advances in imaging technology, as well as the emergence of thrombolytics and subsequent mechanical thrombectomy, sometimes facilitating complete recovery. Increasingly, oral anticoagulants are preventing stroke in patients with atrial fibrillation. Therapies targeting neuroinflammation after brain ischaemia (e.g. transplantation of mesenchymal stem cells) are also emerging as potentially useful.

    Browse our gallery of video highlights and short articles from the conference hub, providing latest expert insights from major conferences and peer-reviewed articles from the journal portfolio.

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    Stroke Content

    Stroke
    Elevation of Serum Oncostatin M Level in Acute Ischaemic Stroke: A Review
    Michael Christian, Youdong Wei

    touchREVIEWS in Neurology. 2024;20(1):1–3:Online ahead of journal publication

    Introduction The term ‘stroke’ is used to describe an adverse clinical state involving interference of blood circulation to the brain due to obstruction or rupture of blood vessels.1 Stroke was previously categorized into a cardiovascular disorder until the release of the International Classification of Disease 11 (ICF-11) in 2018, when stroke was recognized as a neurological […]

    Paediatric Neurology, Stroke, Rare Diseases
    Watch Time: 39 mins
    touchPANEL DISCUSSION
    Contemporary insights on the management of sickle cell disease: Focus on complications and recent advances in therapy
    CE/CME ACCREDITED Prof. Biree Andemariam, Prof. Modupe Idowu, Prof. Mark C Walters

    Three experts discuss the management of complications of sickle cell disease, as well as recent advances in therapy.

    Learning objectives
    Learning Objectives
    • Summarize the various manifestations and multiple complications of SCD
    • Appraise the practical considerations for the multidisciplinary management of SCD complications
    • Interpret the clinical data for established and recently approved therapies for SCD and apply them to clinical practice
    Stroke, Brain Trauma, Neurosurgery
    Watch Time: 34 mins
    touchEXPERT OPINIONS
    Integrating the latest evidence surrounding reversal agents for direct oral anticoagulants for patients experiencing intracerebral haemorrhage into clinical practice
    CE/CME ACCREDITED Prof. Hanne Christensen, Prof. Thorsten Steiner, Dr Truman Milling Translations available:

    Watch three experts provide insights on the impact of ICH in patients receiving DOACs, DOAC-ICH reversal agents and optimizing treatment outcomes.

    Learning objectives
    Learning Objectives
    • Recognize the risk of ICH amongst different patient populations receiving DOACs based on clinical trial and real-world evidence
    • Appraise the latest clinical trial and real-world evidence on the efficacy and safety of oral anticoagulant reversal strategies in the acute management of DOAC-ICH
    • Assess the factors guiding selection and administration of reversal agents and supportive care in the acute management of DOAC-ICH
    Stroke
    Developed by Touch
    Update on the European Stroke Organisation Conference (ESOC) 2023: Peter Kelly
    Watch Time: 6 mins

    The European Stroke Organisation Conference (ESOC) 2023 will take place 24-26 May 2023 in Munich, Germany. The conference will include sessions, plenary lectures, and symposia, covering a wide range of topics related to stroke, including acute management, rehabilitation, imaging, epidemiology, and public health. Prof. Peter Kelly (President, European Stroke Organisation, Dublin, Ireland) joins touchNEUROLOGY to […]

    Stroke
    Watch Time: 48 mins
    touchMDT
    Multidisciplinary insights on the role of GLP-1 RAs in the modern management of stroke in patients with T2D
    CE/CME ACCREDITED Dr Yassir Javaid, Prof. Georgios Tsivgoulis, Prof. Tina Vilsbøll, Ms Hyvelle Ferguson-Davis Translations available:

    A multidisciplinary team and a patient discuss GLP-1 RAs and their role in stroke prevention in patients with T2D.

    Learning objectives
    Learning Objectives
    • Describe the burden of stroke and risk factors for stroke in patients with T2D
    • Evaluate the latest data for GLP-1 RAs in the context of stroke management and prevention
    • Interpret current treatment guidelines for T2D in the context of stroke management and prevention and apply it to clinical practice
    Stroke
    Computed Tomography Perfusion Deficit as an Indicator for Reperfusion in Large-vessel Occlusions with Low National Institutes of Health Stroke Scale Scores in Acute Ischaemic Stroke: A Retrospective Review
    Sachin A Kothari, Uttam Verma, Michael Nahhas

    touchREVIEWS in Neurology 2022;18(2): 147-52 DOI: https://doi.org/10.17925/USN.2022.18.2.147

    In clinical practice, the definition of penumbra is largely based on neuroimaging and indicates potentially salvageable tissue. Perfusion imaging has been useful in identifying this tissue when obeying ‘the mismatch concept’. The mismatch concept is a surrogate marker for salvageable brain tissue and refers to a lesion volume difference (mismatch) between the perfusion deficit (the […]

    Stroke
    Developed by Touch
    Hariklia Proios, Stroke Alliance for Europe (SAFE): Presidential Update

    The Stroke Alliance for Europe (SAFE) is a non-profit-making organisation that represents a range of patient groups from across Europe. Their mutual goal is to drive stroke prevention up the European political agenda and prevent the incidence of stroke through education. touchNEUROLOGY caught up with the SAFE President, Prof. Hariklia (Harriet) Proios, to discuss the […]

    Stroke
    Martin Bretzner - 'Brain-age' biomarkers to predict post-stroke recovery
    Developed by Touch
    Martin Bretzner, ESOC 2022: Brain-age biomarkers to predict post-stroke recovery
    Watch Time: 6 mins

    Brain-age biomarkers can be used to predict post-stroke recovery. Dr Martin Bretzner (Lille Neuroscience & Cognition Research Centre, Lille University Hospital, Lille, France) discusses the results of a study using radiomics, an emerging image-quantifying technology to assess ‘brain-age’ biomarkers. The study investigates how relative brain age, rather than chronological age, can enhance stroke surveillance and […]

    Stroke
    Miquel Lledós - gut microbiome and stroke risk and outcome
    Developed by Touch
    Miquel Lledós, ESOC 2022: The influence of gut microbiome on ischaemic stroke risk and outcome
    Watch Time: 5 mins

    The composition of the gut microbiome is a modifiable factor associated with the risk of ischaemic stroke and post-stroke neurological outcome. Dr Miquel Lledós (Stroke Pharmacogenomics and Genetics Laboratory, Sant Pau Research Institute, Barcelona, Spain) discusses the outcome of a study using faecal samples to demonstrate the influence of the gut microbiome on ischaemic stroke […]

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