Welcome to the latest edition of US Neurology, which features articles covering a wide range of topics relevant to the practice of neurology, and to the wider biomedical community. This issue begins with articles on two progressive diseases of the central nervous system causing motor and cognitive disability: multiple sclerosis (MS) and Parkinson’s disease (PD). Patients with MS express an interest in a more holistic approach to MS management, including diet and exercise, and seek personalized support from knowledgeable practitioners. Dunn et al. report on a recent meeting convened by the National Multiple Sclerosis Society, highlighting challenges and knowledge gaps, and proposing concrete actions to address this important need. Drawing from the observation that MS affects individuals at the peak of their reproductive years, Bove reports recent scientific evidence on pregnancy and MS, and emphasizes the need for a North American MS pregnancy registry, whose focus should include fathers with MS and children of parents with MS. The article by Olanow et al. reports on a symposium highlighting the importance and impact of motor fluctuations (OFF periods) in patients with PD treated with levodopa, and on current and future acute therapies for use during OFF episodes.
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